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C-terminal octapeptide of cholecystokinin decreases food intake in man

The study reported that once-weekly CagriSema resulted in a significant body weight reduction of 13.7% and a higher percentage of patients achieving an HbA1c level of 6.5% or less, confirming the combination's superior efficacy for both weight loss and glycemic control in this population

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Synergies with other metabolic peptides While GLP-1based peptides primarily influence insulin and glucose secretion, amylin analogues like cagrilintide contribute distinct satiety and gastric-emptying signals

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