Key areas of investigation include: Gastrointestinal : Demonstrated protection against NSAID-induced ulcers, inflammatory bowel disease models, and esophageal damage in multiple animal studies Musculoskeletal : Accelerated healing of transected Achilles tendons, quadriceps muscles, and medial collateral ligaments in rat models Neurological : Neuroprotective effects in models of traumatic brain injury, nerve crush injury, and dopaminergic system damage Organ protection : Hepatoprotective, cardioprotective, and nephroprotective effects demonstrated in various toxicity models The primary limitation is that all evidence comes from animal models
FIGURE 5 To further investigate the expression of Ctnnb1 and RNA-seq-identified differentially expressed genes in HFSCs, this study treated HFSCs with 0 mol/L, 10 mol/L, and 20 mol/L of anwuligan, followed by RNA extraction and qRT-PCR analysis
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Dobrucka and the Molecular Imaging Laboratory at the Beckman Institute for use of the IVIS imaging system