tirzepatide instructions for use (KwikPen) Information and Education How to Inject Tirzepatide

However, Byetta and its extended-release version Bydureon BCise were discontinued in 2024

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That's lower than the 7.1% discontinuation rate seen with semaglutide 2.4 mg in the STEP trials, suggesting tirzepatide is better tolerated at maximum doses despite the higher absolute milligram amount

A landmark paper in 2021 describes patients taking 2.4mg (the maximum dose of Wegovy) for 68 weeks, and yielding sustained, clinically relevant weight loss of up to 15%

Your semaglutide dosage in units remains the same on your syringe, but the effective dose you receive may be lower