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Its combination with GLP1R agonists in particular is capable of producing large decreases in weight
Since multiple injections are usually required, the total cost of treatment can be significant
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A recent large genome-wide association study of type 2 diabetes patients who were treated with GLP-1R agonists reported that low-frequency variants of ARRB1 encoding -arrestin were associated with better responses to GLP-1R agonists [25]
Changes in these components lead to heat production or heat loss, reflected by alteration in body temperature (BT)
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