In those patients, addressing the underlying metabolic dysfunction first, through dietary intervention, GLP-1 therapy if indicated, or NAD+ support for cellular energy metabolism, is the clinical priority
Several independent studies have also shown that treatment with arimoclomol, a co-inducer of heat shock proteins, is protective against toxic mutant SOD1 aggregates, delays disease progression and improves motor function in SOD1 G93A mice (Kieran et al., 2004
Drink plenty of water to support detoxification through sweating and urine
However, it is important to consult a healthcare professional before combining it with other medications to avoid potential interactions
Compliance Monitoring Implement strategies to monitor and ensure the subject's compliance with the prescribed dosage regimen, such as participant diaries, regular follow-up visits, and periodic assessments of the remaining spray volume