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Conversely, alternatively activated macrophages (M2), which are favored by Th2 cytokines, including IL-4 and IL-13, promote parasite survival and replication

[5] The most scientifically cautious interpretation is not that broad off-target inhibition has been proven, but that broader non-target effects cannot be excluded when experiments use high concentrations, long exposure windows, sensitive cell systems, or designs lacking orthogonal NNMT validation

Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more

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