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The randomized and placebo-controlled design of all included trials and the double-blind design of most of them can also be other strengths and due to the RCT nature of the studies, the drugs used by the patients (especially in diabetic patients), the diet and the level of physical activity of the participants were controlled and in fact their effects were considered and it can be said that the pure effects of L-carnitine was evaluated

However, anecdotally, those with Mast Cell or histamine intolerances should be wary and work with a practitioner to prime their immune system with other peptides prior to taking BPC 157

Protocol duration varies depending on the peptide, the therapeutic goal, and the individual patient's clinical response

Effects of pycnogenol on ischemia/reperfusion-induced inflammatory and oxidative brain injury in rats