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The population primarily had obesity (Class 1 [BMI 30-35]: 30.9%, Class 2 [BMI 35-40]: 26.2%, and Class 3 [BMI 40+]: 31.5%) compared to overweight (BMI 27-30: 11.3%)
If no bowel movement occurs for 3 or more days, or constipation is accompanied by severe abdominal pain, distension, or vomiting, patients should seek medical evaluation to rule out more serious complications such as ileus or bowel obstruction
Cell 36 , 131140 (2009)
No controlled human data exists for FOXO4-DRI
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