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It also improves baroreflex sensitivity and cardiac autonomic regulation, which are frequently impaired in patients with hypertension (Amorim et al., 2019

Human Evidence Human research primarily involves topical application

Ethics statement The studies involving humans were approved by Institutional Review Board of Jimma University with reference number: IHRPG1/5/2021

I pay attention to that because it tells me they are not just manufacturing a single trending format

It falls under the S0 category of Non-Approved Substances, which is a catch-all classification for any pharmacological substance that isnt approved for human therapeutic use and is not addressed elsewhere on the list