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Neurofibromin 2 expression was significantly reduced in basonclin1-deficient oocytes, while the expression levels of yes-associated protein, TFR, and ACSL4 increased considerably, triggering oocyte ferroptosis (103)
These data could also be used in future studies to improve the kinetics of our sensor by engineering the HT binding pocket, and more generally to design fluorogenic dyes or other robust, targeted sensors
Modulating molecular chaperones improves mitochondrial bioenergetics and decreases the inflammatory transcriptome in diabetic sensory neurons
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