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The enzyme catalyzes the methylation of nicotinamide (a form of vitamin B3) using S-adenosyl-L-methionine (SAM) as a cofactor, producing 1-methylnicotinamide (1-MNA) as a metabolic byproduct
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Subsequent research determined that the scavenger receptor gene family in humans consists of 27 genes
These side effects are as follows: Articular sensitivity Peripheral paresthesia Hyperphagic response Cephalic discomfort Gastrointestinal disturbance Localized dermal reaction at administration site Affective variability Note: Reported side effects in preclinical studies were generally mild and manageable under controlled laboratory conditions
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