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Many nutrients have their action INSIDE the cell, which means that testing serum and blood levels just give us an indication of what may be available but that is assuming everything else is working properly: cellular activity, enzyme activity, receptor activity, etc

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Spine 29 , 26912699 (2004)

Phentermine, the active ingredient in Adipex, works primarily by stimulating the release of noradrenaline (norepinephrine) in the hypothalamus the region of the brain responsible for regulating appetite and energy balance

This suggests that customized regulation of inflammatory pathways may be a more realistic method [178]