Recently, it has been demonstrated that mice with a deletion of the GLP-1 receptor only in -cells, are resistant to the beneficial anti-diabetic effect of a vertical sleeve-gastrectomy ( It appears that only in RYGB and SG patients intestinal derived GLP-1 has a true endocrine role, while in healthy individuals, localized, paracrine and neuronal signals primarily define the GLP-1 physiology
Controversies in the pathogenesis, diagnosis and treatment of PCOS: focus on insulin resistance, inflammation, and hyperandrogenism
It remains in clinical trials
Trends in Immunology, 34 , 137143
Aktualne dane z trwajcych bada wskazuj, e odpowiednimi kandydatami na retatrutyd s na og: Doroli w wieku 18 lat i starsi posiadajcy: BMI 30 kg/m lub wiksze