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Objective evaluations were scored according to spot ultraviolet (UV), spot polarization, skin tone, and efficacy on the medial side of the face photographed using a Janus Facial Analysis System (PIE Co., Ltd, Suwon-si, Gyeonggi-do, Korea), which uses a pigment technology system that assesses the pigment distribution objectively according to three light exposure typesnamely, normal, polarizing, and UV light

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First, LCS3 treatment induced GSH inhibition in VRK2-KO cells, reflected by decreased levels of GSH/GSSG, whereas no significant effect on TXNRD1 activity was verified by the same concentration of LCS3

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