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Disease-modifying therapeutic strategies in osteoarthritis: current status and future directions

In contrast, some BP extracts were examined against gram-negative bacteria which exhibited antibiotic action such as Acinetobacter baumannii and E

Notably, heme oxygenase 1 (HO1), which has a dual role in regulating ferroptosis, oxidizes cellular heme to carbon monoxide, ferrous iron, and biliverdin [25]

Glutathione pool at an elevated level serves to detoxify the damaging effects of increasing ROS, and therefore, is crucial for the adaptation of cancer cells to oxidative stress for optimal survival and growth 16,17