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Interim data from REDEFINE 1 have suggested meaningful body weight reductions in adults with obesity over 68 weeks, comparing favourably with semaglutide alone
While the GLP-1 agonist suppresses appetite, the glucagon agonist increases energy expenditure
The association of smoking status with diabetic microvascular complications in Korean patients with type 2 diabetes
Research status Not FDA-approved
Even if no adverse effects were detected, a larger study will be necessary in order to validate its clinical efficacy (Sufit et al., 2017)
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