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Keywords , MASH , GLP-1 receptor agonists , hepatic steatosis , metabolic dysfunction , tirzepatide , semaglutide , survodutide 0 2 INTRODUCTION Metabolic dysfunction-associated steatotic liver disease (MASLD), previously termed nonalcoholic fatty liver disease (NAFLD), has emerged as the predominant hepatic pathology worldwide, impacting roughly twenty-five percent of the adult population [1,2]

EPR spectroscopy Continuous wave EPR spectroscopy was performed at 20 C with a X-band (9.6346 GHz) spectrometer (EMX-Nano, Bruker Biospin, with a cylindric cavity mode TM1110)

Hierarchical clustering analysis was performed to visualize relative differences in metabolite abundance between groups (Fig

Bands were developed using Clarity Western ECL substrate (Bio-Rad Laboratories, Hercules, CA, USA)

Click here to see semaglutide weight loss before and after pictures.