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The incidence, disability rate and mortality rate of cancer have been increasing, and cancer has become one of the main threats to human health ( 2 GLP-1R and its function Glucagon-like peptide-1 (GLP-1), which is mainly secreted by L cells in the colon and distal small intestine, is a newly discovered glucagon-like peptide-1 that can promote insulin secretion and lower the blood sugar peak more effectively than previously reported ( Therefore, GLP-1 has become an important target for glucose homeostasis regulation

Longer studies and real-world evidence collected through registries are essential

The choice isnt one-size-fits-allit depends on your health, goals, and willingness to navigate the risks and rewards of each path

The 2025 data have now made the evidence far stronger

Recent studies show that GLP-1R is expressed on CD4+ T cells and macrophages, where it shapes T cell differentiation and inflammatory tone ( 1 3 )