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Although these peptides are not FDA-approved, they are widely available through wellness clinics, compounding operations and gray-market online sellers

Shoemaker's research demonstrated that patients with CIRS consistently show severe abnormalities in inflammatory blood markers, including highly elevated TGF-beta1, C4a, and MMP-9, alongside drastically depleted levels of Melanocyte Stimulating Hormone (MSH) and Vasoactive Intestinal Polypeptide (VIP)

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This article traces GHK-Cu from Pickart's discovery through its molecular biology, clinical evidence, gene expression data, and the open questions that remain

doi:10.3390/ijms22168677