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This means it takes a minimum of 16 to 20 weeks just to reach the full therapeutic dose

The elderly are prone to diseases and are often on many prescribed medicines, which can cause insomnia

On average, tirzepatide led to 20.2% weight loss compared to 13.7% with semaglutide over 72 weeks of treatment

Fatigue, constipation and headaches are also possible

Acknowledgements The authors acknowledge Prince Sattam bin Abdulaziz University for supporting this study (University project number PSAU/2025/R/1446)