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PDK is an emerging target for the treatment of MetS which may allow the maintenance of the steady-state concentration of adenosine triphosphate during the feed-fast cycle

4 GST inhibitors and prodrugs are crucial agents that can help reverse multidrug resistance in tumors and increase the therapeutic index of anticancer drugs, which collectively decreases the physical and economic burden of cancer patients

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Within smooth muscle cells (SMC), NO reacts with the heme moiety of a soluble guanylate cyclase (sGC), resulting in activation of the latter and a consequent elevation of intracellular levels of cGMP

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