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Warnings Do not use product if packets printed with lot number are opened

The sustained lipid peroxidation chain reaction results in progressive loss of membrane fatty acids, with consequent decrease in membrane fluidity, increased non-specific permeability to ions, and inhibition of membrane bound receptors and enzymes ( Besides their role in mediating lipid peroxidation, ROS especially nitric oxide (NO ), and OH (92), have also been shown to attach to sperm DNA molecules causing excessive modifications and deletions in their nucleotide bases and strand breakages, along with other multiple genotoxic effects (93)

Elective procedures: if daily dosing, DC on the day of surgery

If anything looks cloudy or has particulates, do not use it

Supply and counterfeit risks Both agents have faced global shortages or stock issues and emerging counterfeit supply chains