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The evidence obtained in multiple randomized clinical trials demonstrates that GLP1RAs are effective for the treatment of type 2 diabetes, obesity, and dyslipidemia
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Dose adjustments are common, and your doctor should monitor blood pressure monthly during GLP-1 treatment, especially in the first 3-6 months when weight loss is most rapid
For someone coming off significant weight loss, the multi-system benefits of this stack can be particularly appealing
Inflammation of the pancreas: upper belly pain, nausea, vomiting Buildup of lactic acid in the body: sudden drop in blood pressure, low body temperature, slow heart rhythm, feeling weak, stomach pain, nausea Kidney problems: urinating less, itching, swelling of the ankles or feet Heart failure: shortness of breath, unusually fast weight gain, swelling of the legs or feet Severe allergic reaction: hives, blisters, trouble breathing, swelling of the face or throat Effects of other drugs, drug classes and over-the-counter products on Janumet XR The following medications may interact with Janumet XR: Carbonic anhydrase inhibitors may increase risk of lactic acidosis Consider more frequent monitoring Drugs that reduce metformin clearance (such as ranolazine vandetanib, dolutegravir, and cimetidine) may increase the accumulation of metformin
