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While patients will notice some significant increases changes in the body after the first month, the full-benefits are usually fully noticed after three to six months of therapy

In this narrative review, we thoroughly trace the current preclinical and clinical evidence of seven pain modalities, including inflammatory pain, osteoarthritis, visceral pain, neuropathic pain, diabetic neuropathy, cancer pain and headache, to support the efficacy and underlying biological mechanisms of GLP-1RAs as therapeutic agents for pain suffering

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Serotonin is responsible for the regulation of mood, memory, sleep, and appetite