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S-5-HT was measured with the HPLC-ECD chromatographic method (38) using a fully clotted sample to accurately take into account the serotonin in circulating platelets
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During the trial, additional anti-diabetic medication was initiated as an add on to randomized treatment by 1.9% and 1.2% of patients randomized to semaglutide tablets 14 mg and empagliflozin 25 mg, respectively
Ginger supplements and vitamin B6 are often suggested as natural alternatives
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