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Tirzepatide is the first combination of entero-pancreatic hormones [dual GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) RA] that has been approved for T2D management based on the findings from the phase 3 SURPASS programme
These side effects typically improve as the body adjusts during the dose escalation period
But the patients who do best are the ones who used their time on the medication to genuinely build healthier habits, who have a clear maintenance strategy in place before their last dose, and who stay connected with their healthcare team throughout the transition
Researchers tracking liver fibrosisthe scarring that signals disease progressionobserved that semaglutide halted or slowed fibrosis development in a subset of NASH patients
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