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Chronic stress and elevated cortisol blunt GLP-1 and insulin responsiveness
What we know today will likely expand significantly in the coming years
Immunohistochemical staining and western blot analysis revealed that SNL increased the activation of microglia and astrocytes in the dentate gyrus of the hippocampus, along with elevated expression of pro-inflammatory cytokines such as TNF-, IL-1 and IL-6, which were significantly reversed by exendin-4 treatment [68]
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