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Since the first semaglutide drug was approved in 2005, patients and manufacturers have seen many changes: shortages, compounding, and more than a thousand lawsuits from patients who experienced severe side effects under these drugs, including stomach paralysis, bowel obstruction, and vision loss

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Back Holst, JJ (26 April 2019) 'From the Incretin Concept and the discovery of GLP-1 to today's diabetes therapy', Frontiers in Endocrinology , 10