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This sensor was used in combination with a redox-sensitive fluorescent protein to quantify redox potential and GSH concentration simultaneously in the endoplasmic reticulum
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Interestingly, repeated NFT treatment resulted in higher GCLC levels in the days after removal of the compound and an elevated induction in response to a second exposure to NFT, similar to the previously published pattern of sulfiredoxin synthesis upon repeated exposure to DEM or tert -butylhydroquinone (Bischoff et al
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