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J Nutr Health Aging
Schmid-Hempel and Ebert 2003
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When used in topical formulations, the most commonly reported issues are localised and mild, and may include: Skin irritation or redness at the site of application Contact dermatitis in individuals with sensitive skin or known peptide sensitivities Scalp itching or tingling , which may be transient The following precautions are advised: Avoid application to broken, inflamed, or irritated skin , and keep the product away from the eyes and mucous membranes
In addition, overexpression of miR-296 is also associated with the disease and causes thyroid cell enlargement (Pu And Zhang 2024)
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