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Improvement should require a coherent pattern: pathway marker change, stable renal and nutritional context, parallel improvement in imaging or function, and absence of compensatory harm in another metabolic axis
With B12 shots, bioavailability is at its peak
However, the use of certain drugs may result in the abnormal excretion of betaine from the body
These may include injection site discomfort or mild swelling, occasional headache, or mild fatigue, particularly with appropriate dosing and patient preparation including adequate hydration
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