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The gut microbiota may be interacting with the other pathways such as inflammation, or endocrine which then interact with and affect the integrity of the BBB, but either way it is now apparent that the gut microbiota is a modulator of BBB integrity

For the treatment policy estimate, missing data were imputed using outcomes from participants who discontinued treatment but completed the week 26 visit [1]

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Finally, the purified nuclear and cytoplasmic fractions were boiled in 60 L of 2 SDS loading buffer (Cat# P0015L