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Targeting MDSCs has therefore emerged as a promising strategy to enhance immunotherapy efficacy, and nanomedicine platforms designed to deplete or reprogram these cells are under active investigation ( CAFs represent a third critical component of the immunosuppressive TME

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[1] [3] The injection bypasses the gastrointestinal tract entirely, making it particularly effective for patients with absorption problems such as pernicious anaemia or those who have undergone gastric surgery