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1 HF is commonly categorised according to left ventricular ejection fraction ranges into HF with reduced ejection fraction (HFrEF), HF with mildly reduced ejection fraction (HFmrEF) and HF with preserved ejection fraction (HFpEF), each of which has distinct possible pathophysiological mechanisms

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This is a realistic and commonly reported outcome

Converts white adipose tissue into brown adipose tissue (a phenomenon called fat tissue browning) to prevent body disfigurement associated with obesity and overweight

Activation of the hypothalamic GIPR suppresses food intake 11,12