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The excessive accumulation of D-2HG, a tumor-specific metabolite, contributes to the formation of malignant gliomas
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We can diagnose and treat lumbar facet joint pain due to spondylosis similarly, either with a steroid injection into the joint (intra-articularly) or by blocking small nerves to these joints (medial branch blocks) with local anesthetic diagnostically and, if warranted, with RFA therapeutically (as a treatment)
10.1371/journal.pbio.0050172 PLoS Biol
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