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Research suggests that it increases melatonin levels in the body and improves sleep

10.1111/dom.15342 Summary Keywords cardiovascular safety, FAERS, heart failure, pharmacovigilance, tirzepatide Citation Chen D, Wang Z, Xie Z, Chen Y, Luo S and Xu S (2026) Cardiovascular adverse event reporting profile of tirzepatide: a real-world pharmacovigilance analysis of heart failure, arrhythmias, and ischemic events

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