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Persistent vomiting or diarrhoea can lead to dehydration, which in turn may increase the risk of acute kidney injury a class-relevant concern also noted in the Summary of Product Characteristics (SmPC) for approved GLP-1 receptor agonists such as semaglutide
A systematic review and network meta-analysis of randomized controlled trials evaluating the evidence base of melatonin, light exposure, exercise, and complementary and alternative medicine for patients with insomnia disorder
Gilstrap LG, Blair RA, Huskamp HA, Zelevinsky K, Normand SL
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