Our findings may have wide implications for human health
With sufficient glutathione present, NAPQI is very quickly metabolized into sulfate and cysteine compounds, which are readily excreted through the kidneys.[ref] However, when it isnt neutralized, NAPQI is highly reactive and can cause oxidative stress and damage to the liver cells, hepatocytes, leading to cell death
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doi:10.1111/j.1529-8027.2012.00390.x 22Hoffman-SnyderC, SmithBE, RossMA, HernandezJ, BoschEP