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JAMA 1973

Accumulated mtDNA fragments have been shown to activate the cyclic GMP-AMP synthase-stimulator of interferon genes (cGAS-STING) pathway in chondrocyte models, promoting the expression of senescence-related markers such as p16INK4a and p21Cip1/Waf1, and inducing a senescent phenotype (60)

Additionally, glutathione helps the liver process toxins, which are essential for overall wellness and resilience against environmental and dietary stressors