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Very common (more than 1 in 10): mild pain, redness, or swelling at injection site usually fades in a day

Although certain bacteria in the human colon synthesize small amounts, the absorbed quantity is inadequate to meet the bodys needs

Physical Symptoms of Vitamin B12 Deficiency Fatigue and weakness Pale skin Shortness of breath Nerve problems Mouth ulcers Digestive issues Vision problems Mobility difficulties Cognitive Symptoms of Vitamin B12 Deficiency Peripheral Neuropathy Cognitive Disturbances Memory Problems Reversible Dementia Confusion Decreased Problem Solving Psychiatric Symptoms of Vitamin B12 Deficiency Depression Anxiety Intrusive Thoughts Irritability Psychosis Inattention Insomnia Panic attacks Treatment of Vitamin B12 Deficiency It has been observed that oral administration of high-dose vitamin B12 (1 to 2 mg daily) is as effective as intramuscular administration for correcting anemia and neurologic symptoms

This becomes especially important in studies requiring frequent administration

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