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Moreover, curcumin modulates the gutbrain axisit reshapes microbiota composition, strengthens intestinal and bloodbrain barriers, and prevents bacterial endotoxins like LPS from triggering central inflammation

It is produced by the liver and plays a crucial role in many body processes

It is ideal for individuals dealing with sun damage or skin discolouration

53 Furthermore, elevated cholesterol levels in the microenvironment stimulate the expression of immune checkpoints, including PD-1, 2B4, TIM-3, and LAG-3, in T cells, driving T-cell exhaustion via the activation of the endoplasmic reticulum stress response

The cell membrane was collected by centrifugation at 25,000 g for 30 min at 4 C