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Yes, and many researchers consider this the optimal approach
Genetic deletion of GPX4 is embryonic lethal [14, 15], and conditional deletion of GPX4 in brain results in severe neurodegeneration [16], indicating that the role of GPX4 in lipid hydroperoxide removal is essential for cell viability
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Although often used interchangeably with the term folate, there are some notable differences between these two compounds that are not to be overlooked
doi: 10.1021/acsomega.0c00834 68 LiZShiMLiNXuR
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