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R471C has been shown to localise to the membrane and has ~15% activity of wildtype OCTN2 in CHO cells, which is consistent with the observed reduction in currents for R471A, meanwhile Y358N in CHO cells has ~8% activity, though localisation data for Y358N is unavailable 11,50
Ng, Journal (Endocrinology, Volume 142, Issue 12, December 2001, Pages 51825189)
Reconstitution & Handling in Research Settings Both BPC 157 and TB 500 are supplied in lyophilized (freeze-dried) powder form for research purposes
Mazziotti, G., Canalis, E
Furthermore, a critical remaining gap in current translational research is the lack of stage-specific and pathway-specific efficacy data for established therapeutic agents
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