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These measurements allow the calculation of the ratio of GSH/GSSG, or the ratio of reduced to oxidized glutathione, in order to determine the oxidative stress present in cultured mammalian cells in response to a compound

The first step in the synthesis of GSH is the formation of -glutamyl-cysteine (GluCys) from the constituent amino acids glutamate and cysteine by the enzyme -glutamyl-cysteine synthetase (GCS, also called glutamate cysteine ligase (GCL))

At 10 units (0.1 mL): 250 mcg of each

The human evidence is limited, but the mechanistic rationale is enough that this remains an active research area

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