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For context on how long GI and other side effects tend to last on GLP-1 treatment including during and after use the article on how long GLP-1 side effects last summarizes what research and patient reports suggest

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Amylin's primary physiological functions include [11] : Slowing gastric emptying: Delays the rate at which food enters the small intestine, reducing post-meal glucose spikes Controlling glucose metabolism: Reduces inappropriate hepatic glucose output during meals Promoting satiety: Acts on area postrema in the brainstem to reduce food intake In type 2 diabetes, amylin secretion is impaired alongside insulin deficiency, contributing to postprandial hyperglycemia and dysregulated satiety [12]