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Retatrutide (15 mg) is a weight loss and metabolic peptide classified as a synthetic investigational compound studied in metabolic and cellular signaling research

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Germ-free murine models (Yang et al., 2017) confirm that microbiota deprivation increases GLP-1R + cells and prolongs gastrointestinal transit, whereas fecal microbiota transplantation normalizes GLP-1 secretion and motility, underscoring microbial indispensability in sustaining the GLP-1-ENS signaling axis