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Many people start to notice weight loss within a few weeks, but the speed at which you lose weight will depend on a range of factors, including your starting weight, your daily habit changes (including changes to your calorie intake and how much physical activity you get), and other factors like any underlying conditions you might have

In January 2026, Novo Nordisk, the makers of Ozempic (semaglutide), released the drug as daily oral pill

In clinical trials, adding medication to lifestyle intervention produced larger average weight loss than placebo plus lifestyle alone, but individual results vary and side effects can limit adherence