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Studies show that individuals who gradually reduced their dose maintained a stable weight for at least six months after stopping, compared to those who stopped suddenly
For confirmed deficiency or pernicious anaemia, NICE Clinical Knowledge Summaries recommend hydroxocobalamin 1mg intramuscularly, with frequency determined by the underlying cause and neurological involvement
Similarly, the CONQUER trial found that people on mid and maximum doses lost around 7% and 9% more weight, respectively, than the placebo group
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