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Is a maintenance dose of Wegovy a good idea
The Arg3 substitution replaces one amino acid (arginine at position 3), making the compound less likely to bind to IGF-binding proteins that normally deactivate IGF-1 in the bloodstream
At the highest dose studied, retatrutide also produced weight loss approaching the range often seen after bariatric surgery, although surgery and medication should not be viewed as equivalent treatments
Brand-name semaglutide (Wegovy or Ozempic) cost between $499 to $1,500+ per month without insurance
The placebo group had merely a 2% average weight loss
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