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As glycemic control improves and glucose levels normalize, this effect should actually decrease

Magnesium Powerful antioxidant that helps protect cells from damage, supports detoxification in the liver, boosts immune function, and promotes skin health by reducing oxidative stress

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If SAH accumulates, homocysteine is poorly managed or sulfur-amino-acid substrate is inadequate, the liver may have less flexibility to maintain methylation while also supplying cysteine for glutathione and taurine

This illustrates that for almost any treatment, including B vitamin supplements, one size does not fit all, and that lack of an overall effect in a study population does not necessarily mean there are not individuals within that population who might benefit